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and borders Butler, Montgomery, and Darke counties in Ohio and Wayne County in Indiana. Strategically located in southwest Ohio along the Indiana border and is conveniently positioned on the east to west spine of America's highway system--Interstate 70 Corridor of the Future.This strategic location affords easy access to a network of interstate highways and major state routes, Preble County is ideal for major transportation between Indianapolis and Columbus as well as within the Dayton-Cincinnati region and beyond.
Preble County's location along I-70 and I-75  is ideal for distribution, logistics, and a network of interstates that puts your business on a corridor of a diverse group of industries including biotechnology, pharmacology, manufacturing technology, advanced materials, packaging, aerospace, and information technology.
Preble County's location between the cities of Indianapolis, Columbus, Dayton and Cincinnati on Interstate 70 and 75, makes it a prime location in a market with a population of more than 3 million.
Preble is within a one-day drive to 20 major metro markets including Atlanta, Charlotte, Chicago, Detroit, Nashville, Milwaukee, Pittsburgh, St. Louis, Toronto and Washington DC. The County is also within 600 miles of 64% of the nation's population and 53% of the country's manufacturing plants.
Preble County, Ohio is part of the Dayton Metropolitan Statistical Area (MSA), the fourth largest metro area in Ohio and the 61st largest metro area in the United States as defined by the U.S. Census Bureau.  Preble County neighbors Butler County and the larger Cincinnati-Middletown, OH-KY-IN (MSA).  The Dayton five metropolitan statistical areas has more than 300 towns, villages and cities, is also the nation's tenth largest "90-minute" land market, with more than 5.6 million people living within a 90-minute drive.
As the larger cities in the region continually expand, Preble County is rapidly becoming an ideal location for corporations to produce and move materials easily around the Midwest and the rest of the nation with easy access to key interstate, railroad, and air travel points. Residents can easily enjoy all of the cultural and entertainment amenities of several moderate to large, clean, model Midwestern cities, while immediately surrounded by the peaceful calm of beautiful countryside.(1)
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Sources:
1. Preble County Commissioners Website  (http://www.prebco.org)